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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
18.48
Human Site:
S1739
Identified Species:
31.28
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1739
Q
L
P
S
L
M
P
S
L
L
T
T
M
K
N
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1739
Q
L
P
S
L
M
P
S
L
L
T
T
M
K
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S1736
Q
L
P
S
L
M
P
S
L
L
T
R
M
K
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S1738
Q
L
P
S
L
M
P
S
L
L
T
A
M
K
S
Rat
Rattus norvegicus
NP_001101888
2143
241191
S1738
Q
L
P
S
L
M
P
S
L
L
T
A
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
A1750
Q
L
P
R
L
M
P
A
L
L
K
T
L
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
A1742
Q
L
H
R
L
M
P
A
V
L
D
T
L
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
Q1686
Q
L
P
K
F
A
P
Q
L
T
E
L
L
K
E
Honey Bee
Apis mellifera
XP_393800
2028
231830
A1609
S
L
N
K
F
V
P
A
I
L
R
L
L
E
D
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
T1274
N
Q
P
S
S
S
T
T
A
A
F
Q
G
G
S
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
L1259
W
Q
R
V
M
T
I
L
E
N
L
Q
Q
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
V1605
V
L
V
T
L
E
A
V
I
D
K
L
G
G
F
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
K1393
A
D
S
S
N
P
L
K
E
Q
L
Q
V
A
I
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L1412
A
E
K
P
D
G
A
L
H
N
A
A
Y
A
F
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
73.3
N.A.
53.3
N.A.
40
20
13.3
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
73.3
N.A.
46.6
60
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
15
22
8
8
8
22
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
8
8
0
0
0
8
% D
% Glu:
0
8
0
0
0
8
0
0
15
0
8
0
0
8
15
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
8
0
0
0
15
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
15
15
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
15
0
0
0
8
0
8
% I
% Lys:
0
0
8
15
0
0
0
8
0
0
15
0
0
58
8
% K
% Leu:
0
72
0
0
58
0
8
15
50
58
15
22
29
0
0
% L
% Met:
0
0
0
0
8
50
0
0
0
0
0
0
29
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
15
0
0
0
0
29
% N
% Pro:
0
0
58
8
0
8
65
0
0
0
0
0
0
0
0
% P
% Gln:
58
15
0
0
0
0
0
8
0
8
0
22
8
0
0
% Q
% Arg:
0
0
8
15
0
0
0
0
0
0
8
8
0
8
0
% R
% Ser:
8
0
8
50
8
8
0
36
0
0
0
0
0
0
22
% S
% Thr:
0
0
0
8
0
8
8
8
0
8
36
29
0
0
0
% T
% Val:
8
0
8
8
0
8
0
8
8
0
0
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _